“FLip” mutations

Facts for Prelims (FFP) Source: DTE  Context:  The omicron subvariant JN.1, characterized by the “FLip” mutation L455S in its spike protein, is expected to become the dominant lineage of the SARS-CoV-2 virus worldwide. This subvariant, a descendant of the BA.2.86 lineage, has shown rapid growth and was designated a variant of interest (VOI). The “FLip” …