Bioactive Peptides

Source:  PIB

Context: A study by the Institute of Advanced Study in Science and Technology (IASST), Guwahati, has shown that bioactive peptides in fermented foods can have population-specific health benefits, paving the way for personalised nutrition in India.

About Bioactive Peptides:

  • What it is?
    • Short protein fragments (2–20 amino acids) formed during fermentation of foods such as yogurt, idli, miso, kimchi, natto, and fermented fish.
    • Known for antimicrobial, antihypertensive, antioxidant, and immune-modulatory properties.
  • Aim:
    • To assess the health benefits of BAPs in regulating blood pressure, blood sugar, immunity, and inflammation.
    • To explore precision nutrition solutions tailored to India’s genetically and culturally diverse population.
  • Key Features:
    • Mechanism: Interact with biomolecules via electrostatic forces, hydrogen bonds, and hydrophobic interactions.
    • Health Impact: Influence cardiac function, metabolic health, and immune response.
    • Personalised Response: Effectiveness varies due to genetic polymorphisms (e.g., ACE, IL-6), gut microbiota differences, and dietary habits.
    • Research Tools: Encourages use of omics-based approaches for deeper analysis.
  • Significance:
    • Public Health Potential: Can be integrated into dietary guidelines to address hypertension, diabetes, and immunity-related disorders.
    • Cultural Relevance: Promotes India’s traditional fermented foods in global nutrition science.