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Recombinant Proteins

Facts for Prelims (FFP)

 Context: Researchers at the Indian Institute of Science (IISc), Bengaluru, have devised a ground-breaking method for mass-producing recombinant proteins, which include vital substances like vaccine antigens, insulin, and monoclonal antibodies.


What are Recombinant Proteins?

They are proteins that are artificially produced through genetic engineering techniques. These proteins are created by introducing specific DNA sequences, encoding desired protein products, into host organisms such as bacteria, yeast, or mammalian cells. The host cells then use their own cellular machinery to produce the recombinant proteins according to the inserted genetic instructions.


Recombinant proteins have a wide range of applications, including in medicine (such as vaccine antigens, insulin, and therapeutic antibodies), agriculture, industry, and research. They are crucial for various biotechnological and pharmaceutical purposes due to their precise control over protein structure and function.


What are Proteins?

Proteins serve as the backbone of biological systems, driving essential processes like gene expression, cell growth, and communication within cells. The blueprint for protein synthesis resides in DNA, guiding the tightly regulated transcription process to generate messenger RNA (mRNA) for protein production.

Source: Th