Facts for Prelims (FFP)
Source: TH
Context: AI has significantly enhanced the efficiency and speed of drug development, a traditionally costly and time-consuming process.
AI Tools in Drug Development:
AlphaFold 3 and RoseTTAFold All-Atom:
- Developers: AlphaFold is developed by DeepMind, a Google company, and RoseTTAFold by the University of Washington.
- Functionality: These tools use deep neural networks to predict the three-dimensional structures of proteins and their interactions with drugs. They provide a major leap in predicting not just static protein structures but also dynamic interactions with various biological molecules, including DNA, RNA, and small molecules.
- Performance: In tests, AlphaFold 3 accurately predicted drug interactions 76% of the time, outperforming RoseTTAFold All-Atom at 40%.
