Lathyrism

Facts for Prelims (FFP)

 

Source: DTE

 Context: Grass pea, also known as khesari dal, has been historically infamous for causing lathyrism, a neurological disease leading to lower limb paralysis. 

  • In the late 19th century, an outbreak of lathyrism linked to grass pea led to its ban in India in 1961 under the Prevention of Food Adulteration Act.
  • Despite the ban, grass pea cultivation continued, and researchers developed low-toxin varieties.
  • In 2015, an expert committee recommended lifting the ban, emphasizing its potential for food security amid climate change.

 

Lathyrism is a neurological disorder caused by eating too much grass pea (Lathyrus sativus). It’s also known as neurolathyrism

Lathyrism is one of the oldest known neurotoxic disorders. It’s a skeletal disorder caused by the toxin BAPN, which inhibits the copper-containing enzyme lysyl oxidase