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Umbilical Cord blood and its significance:

GS Paper 3:

Topics Covered: Biotechnology related issues.

 

Context:

A US woman has been cured of HIV after receiving a transplant of umbilical cord blood

  • She has become the third person in the world, and the first woman, to be cured of HIV.

 

What is HIV and how is it transmitted?

  • Human immunodeficiency virus or HIV is an infection that attacks the immune system by destroying the body’s immune cells called CD4, which help it respond to infection.
  • Once HIV attacks the CD4 cells, it starts replicating and destroying the cells, weakening the body’s immune system and making it more prone to certain “opportunistic infections” that take advantage of the weak immune system.

 

Why is this significant?

  • This was the first time an umbilical cord blood transplant was successfully carried out on an HIV patient. This approach is likely to make treatment more widely available.
  • Since this breakthrough treatment only requires partial matches and not exact matches, it opens up treatment options for people from diverse racial backgrounds.

 

What is Cord Blood?

Cord blood (short for umbilical cord blood) is the blood that remains in the umbilical cord and placenta post-delivery.

  • It contains special cells called hematopoietic stem cells that can be used to treat some types of diseases.

 

What is Cord blood banking?

Cord blood banking is the process of collecting the cord blood and extracting and cryogenically freezing its stem cells and other cells of the immune system for potential future medical use.

  • Globally, cord blood banking is recommended as a source of hematopoietic stem cell transplantation for haematological cancers and disorders where its use is recommended.
  • For all other conditions, the use of cord blood as a source of stem cells is not yet established.

 

What Can It Be Used For?

The umbilical cord fluid is loaded with stem cells.

  • They can treat cancer, blood diseases like anemia, and some immune system disorders, which disrupt your body’s ability to defend itself.
  • The fluid is easy to collect and has 10 times more stem cells than those collected from bone marrow.
  • Stem cells from cord blood rarely carry any infectious diseases and are half as likely to be rejected as adult stem cells.

 

Concerns associated with stem cell banking:

  • Over the past decade, stem cell banking has been aggressively marketed even as its use is still in experimental stages. But these companies charge enormous fees from parents to preserve cells.
  • The concern here is that it is merely by emotional marketing that companies convince parents to bank the cells for several years promising future therapeutic use.

 

InstaLinks:

Prelims Link:

  1. What are stem cells?
  2. Types of stem cells?
  3. Their benefits?
  4. What is stem cell therapy?
  5. Various projects in this regard.

Mains Link:

What is cord blood? How to- be parents are falling prey to the emotional marketing tactics by stem cell banking companies? Discuss.

Sources: Indian Express.