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RT-LAMP based test for Coronavirus

RT-LAMP based test for Coronavirus

What to study?

For Prelims and Mains: RT- LAMP- key features and significance of the RT- LAMP based tests.

Context: CSIR-IIIM & Reliance Industries Limited (RIL) to develop RT-LAMP based test for Coronavirus.

What is Reverse Transcriptase-Loop Mediated Isothermal Amplification (RT-LAMP) test?

COVID-19 RT-LAMP test is a nucleic acid based test carried out from nasal/throat swab sample from patients.

 Benefits:

  • It is rapid (45-60 min), cost effective and accurate test.
  • The advantage of this test is that the RT-LAMP based COVID-19 kit components are easily available and these can be completely manufactured in India.

rapid_test

Difference between RT- PCR and RT- LAMP:

While the current COVID-19 testing is done by real-time PCR their components are mostly imported. Further these tests are expensive; require highly trained manpower, costly instruments and a relatively high-end lab and cannot be deployed at remote locations in quarantine centers, airports and railway stations, etc.

On the other hand, the RT-LAMP test can be done in a single tube with minimal expertise in a very basic lab setup like mobile units / kiosks for testing at Airports, Railway Stations, Bus Stands and other public places.

Significance:

With the formal launch of the RT-LAMP based diagnostic test, the COVID-19 testing will not only be more rapid, cheap, easy and accessible but also would go a long way quickly isolating the infected individuals and mitigating the spread of virus.

Sources: pib.